Oleoyl chloride → N-[4-(Oleoyloxy)phenyl]-3-[N-(2,4-diacetoxy-3,3-dimethyl-1-oxobutyl)amino]propanamide
Reaktionsgleichung
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9](=[O:28])[CH2:10][CH2:11][NH:12][C:13](=[O:27])[CH:14]([O:23][C:24](=[O:26])[CH3:25])[C:15]([CH3:22])([CH3:21])[CH2:16][O:17][C:18](=[O:20])[CH3:19])=[CH:4][CH:3]=1.[C:29](Cl)(=[O:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]/[CH:37]=[CH:38]\[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]>>[C:29]([O:1][C:2]1[CH:3]=[CH:4][C:5]([NH:8][C:9](=[O:28])[CH2:10][CH2:11][NH:12][C:13](=[O:27])[CH:14]([O:23][C:24](=[O:26])[CH3:25])[C:15]([CH3:22])([CH3:21])[CH2:16][O:17][C:18](=[O:20])[CH3:19])=[CH:6][CH:7]=1)(=[O:47])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]/[CH:37]=[CH:38]\[CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH3:46]Komponenten
3
Versuchsvorschrift
N-(4-hydroxyphenyl)-3-[N-(2,4-diacetoxy-3,3 -dimethyl-1-oxobutyl)amino]propanamide (394 mg) and 301 mg of oleoyl chloride were reacted in the same manner as in Example 6 to obtain 530 mg of the title compound (yield 81%)
Quellen und Nachweise
- ORD-Eintrag
- ord-5ee50ee22cfc492fb8569071e6774dbc