2-Bromopropan-1-ol → Phosphorodichloridic acid-2-bromopropyl ester

HRID 893582Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 893582
[P:1]([Cl:5])(Cl)([Cl:3])=[O:2].[Br:6][CH:7]([CH3:10])[CH2:8][OH:9]>C(Cl)(Cl)(Cl)Cl>[Br:6][CH:7]([CH3:10])[CH2:8][O:9][P:1]([Cl:5])([Cl:3])=[O:2]

Komponenten

4

Edukt 2

HCID 117132-Bromopropan-1-olHCID 24813Phosphorus oxychloride

Produkt 1

HCID 14256196Phosphorodichloridic acid-2-bromopropyl esterAusbeute 56,7 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 5943Carbon TetrachlorideLösungsmittel2×

Versuchsvorschrift

To a solution of 42 g of phosphorous oxychloride in 110 ml of carbon tetrachloride was added dropwise with stirring a solution of 25 g of 2-bromo-1-propanol in 25 ml of carbon tetrachloride. This mixture was stirred overnight, then taken to dryness, evaporated twice from toluene and dried. The residue was distilled on a Kugelrohr 75° C., 0.05 mm, giving 26.1 g of the desired compound as a colorless oil.

Aufarbeitung

  1. customevaporated twice from toluene
  2. customdried
  3. distillationThe residue was distilled on a Kugelrohr 75° C., 0.05 mm

Quellen und Nachweise

ORD-Eintrag
ord-788e949a73a34870b5b7861e89959dc4
Quelldatensatz
uspto-grants-1992_06
Patentnummer
US05126291

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