3-Allyl-4-methyl-4,5-epoxypentan-2-one → 2,4-Dimethyl-3-(prop-2-en-1-yl)furan

HRID 894157Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 894157
[CH2:1]([CH:4]([C:8]1([CH3:11])[O:10][CH2:9]1)[C:5](=O)[CH3:6])[CH:2]=[CH2:3]>C(=O)([O-])[O-].[Na+].[Na+]>[CH3:11][C:8]1[O:10][CH:9]=[C:5]([CH3:6])[C:4]=1[CH2:1][CH:2]=[CH2:3]

Komponenten

3

Edukt 1

HCID 132086283-Allyl-4-methyl-4,5-epoxypentan-2-one

Produkt 1

HCID 132086342,4-Dimethyl-3-(prop-2-en-1-yl)furanAusbeute 45,3 %

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 10340Sodium CarbonateLösungsmittel

Versuchsvorschrift

3-Allyl-4-methyl-4,5-epoxy-pentan-2-one (4.50 g) was added to a 1% aqueous sodium carbonate solution (150 ml), followed by stirring for 2 hours at a bath temperature of 60° to 65° C. The reaction solution was extracted three times with methylene chloride, and the methylene chloride layer was washed with an aqueous sodium chloride solution. After removing the solvent by evaporation, the residue was column chromatographed on silica gel (50 g) and developed with methylene chloride. From the first eluate (400 ml) was obtained 1.80 g of a pure objective 2,4-dimethyl-3-allylfuran.

Aufarbeitung

  1. extractionThe reaction solution was extracted three times with methylene chloride
  2. washthe methylene chloride layer was washed with an aqueous sodium chloride solution
  3. customAfter removing the solvent
  4. customby evaporation
  5. customchromatographed on silica gel (50 g)

Quellen und Nachweise

ORD-Eintrag
ord-6e38610a068c406181689ecfda0b98dd
Quelldatensatz
uspto-grants-1981_08
Patentnummer
US04282372

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