HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Tetrahydrofuran → 6,11-Dihydro-11-hydroxydibenz[b,e]oxepin-2-carboxylic Acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Tetrahydrofuran | HCID 8028 | — |
| Edukt | Sodium Hydroxide | HCID 14798 | — |
| Edukt | Methyl 11-hydroxy-6,11-dihydrobenzo[c][1]benzoxepine-2-carboxylate | HCID 2769059 | — |
| Lösungsmittel | Water | HCID 962 | — |
| Produkt | 6,11-Dihydro-11-hydroxydibenz[b,e]oxepin-2-carboxylic Acid | HCID 12929144 | — |
Reaktionsschritte
Dissolve 900 mg. of methyl 6,11-dihydro-11-hydroxydibenz[b,e]oxepin-2-carboxylate in 20 cc. of tetrahydrofuran. Add 20 cc. 1 N aqueous sodium hydroxide. Stir at room temperature for 48 hours. Dilute with water and extract with ether. Acidify the aqueous fraction with hydrochloric acid and extract with ether. Evaporate the organic phase to obtain the title product (m.p. 275° C. dec.).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04282365 |
| Quelldatensatz | uspto-grants-1981_08 |
| ORD ID | ord-06261300041049b7ae1e5f982962a19a |
| Quellennotiz | uspto-grants-1981_08 |