Thionyl Chloride → 6,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

HRID 895005Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 895005
[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13](O)=[O:14])[C:5]2=[O:16].S(Cl)([Cl:19])=O>>[OH:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[OH:12])[O:8][CH:7]=[C:6]([C:13]([Cl:19])=[O:14])[C:5]2=[O:16]

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 122007766,7-Dihydroxychromon-3-carboxylic acid

Produkt 1

HCID 127657576,7-Dihydroxy-4-oxo-4H-1-benzopyran-3-carbonyl chloride

Versuchsvorschrift

A mixture of 6,7-dihydroxychromone-3-carboxylic acid (888 mg, 4 mmol) and thionyl chloride (25 ml) was refluxed for one hour and the thionyl chloride was evaporated. After the addition of benzene, the mixture was evaporated again to dryness and the residue was triturated with dichloromethane to give the desired compound (719 mg).

Aufarbeitung

  1. temperaturewas refluxed for one hour
  2. customthe thionyl chloride was evaporated
  3. additionAfter the addition of benzene
  4. customthe mixture was evaporated again to dryness
  5. customthe residue was triturated with dichloromethane

Quellen und Nachweise

ORD-Eintrag
ord-94016eef1a974e3db1fd86761d3233ff
Quelldatensatz
uspto-grants-1981_08
Patentnummer
US04285941

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