Thionyl Chloride → 7,8-Dihydroxychromone-3-carbonyl chloride

HRID 895007Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 895007
[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13](O)=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1.S(Cl)([Cl:19])=O>>[OH:1][C:2]1[C:11]([OH:12])=[C:10]2[C:5]([C:6](=[O:16])[C:7]([C:13]([Cl:19])=[O:14])=[CH:8][O:9]2)=[CH:4][CH:3]=1

Komponenten

3

Edukt 2

HCID 24386Thionyl ChlorideHCID 127658447,8-Dihydroxychromone-3-carboxylic acid

Produkt 1

HCID 130830427,8-Dihydroxychromone-3-carbonyl chloride

Versuchsvorschrift

A mixture of 7,8-dihydroxychromone-3-carboxylic acid (6.6 g, 30 mmol) and thionyl chloride (25 ml) was refluxed for one hour, and the thionyl chloride was removed. After the addition of benzene to the residue, the mixture was evaporated to dryness and the residue was triturated with n-hexane to give the desired compound (7.2 g).

Aufarbeitung

  1. temperaturewas refluxed for one hour
  2. customthe thionyl chloride was removed
  3. additionAfter the addition of benzene to the residue
  4. customthe mixture was evaporated to dryness
  5. customthe residue was triturated with n-hexane

Quellen und Nachweise

ORD-Eintrag
ord-602cf728945244e888a8c3d8c9278467
Quelldatensatz
uspto-grants-1981_08
Patentnummer
US04285941

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