Hydrochloric Acid → HCID 12112012, Verbindung
Reaktionsgleichung
[C:1]1([C:11]([N:13]2[C:17](=[O:18])[C:16]([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)([C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)[N:15]([CH2:31][C:32]([O:34]C(C)(C)C)=[O:33])[C:14]2=[O:39])=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1.Cl>FC(F)(F)C(O)=O.ClCCl>[C:1]1([C:11]([N:13]2[C:17](=[O:18])[C:16]([C:19]3[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=3)([C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[N:15]([CH2:31][C:32]([OH:34])=[O:33])[C:14]2=[O:39])=[O:12])[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3][CH:2]=1Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
tert-Butyl 2-(3-naphthylcarbonyl-2,4-dioxo-5,5-diphenylimidazolidinyl)acetate (300 mg) was dissolved in a 20% trifluoroacetic acid/dichloromethane solution (2 mL), and the solution was stirred at room temperature overnight. After a 1N aqueous hydrogen chloride solution was added, the solution was extracted three times using chloroform (50 mL). The resulting organic layer was washed with a saturated brine, and dried over anhydrous magnesium sulfate, and the solvent was distilled off. Further, recrystallization from IPE afforded 231 mg of white crystals.