5,12-Naphthacenedione → Doxorubicin

https://huagongshe.com/de/reaction/896754

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5,12-Naphthacenedione	HCID 14160	—
Edukt	Doxorubicin Hydrochloride	HCID 443939	—
Produkt	Doxorubicin	HCID 31703	—

Reaktionsschritte

Doxorubicin hydrochloride, 5,12-Naphthacenedione, (8s-cis )-10-((3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-hydrochloride (hydroxydaunorubicin hydrochloride, Adriamycin) is used in a wide antineoplastic spectrum. It binds to DNA and inhibits nucleic acid synthesis, inhibits mitosis and promotes chromosomal aberrations.

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US06919425B2
Quelldatensatz	uspto-grants-2005_07
ORD ID	ord-185936a3f50f4939bef25820a960271d
Quellennotiz	uspto-grants-2005_07