Sodium Hydroxide → 4-(Cyanomethyl)benzoic acid

HRID 898533Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 898533
[C:1]([CH2:3][C:4]1[CH:14]=[CH:13][C:7]([C:8]([O:10]CC)=[O:9])=[CH:6][CH:5]=1)#[N:2].[OH-].[Na+]>C(O)C>[C:1]([CH2:3][C:4]1[CH:14]=[CH:13][C:7]([C:8]([OH:10])=[O:9])=[CH:6][CH:5]=1)#[N:2]

Komponenten

4

Edukt 2

HCID 14798Sodium HydroxideHCID 11989373ethyl 4-(cyanomethyl)benzoate

Produkt 1

HCID 2708714-(Cyanomethyl)benzoic acid

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 702EthanolLösungsmittel

Versuchsvorschrift

A solution of 10 g (53 mol) of ethyl 4-cyanomethyl-benzoate and 2.02 mL of a 1 M sodium hydroxide solution in 100 mL of ethanol is refluxed for one hour. Then the reaction solution is evaporated down and the residue is combined with ice water. Concentrated hydrochloric acid is added dropwise to the reaction solution until no more precipitate is formed. The precipitate is filtered off, washed twice with water and dried.

Aufarbeitung

  1. customThen the reaction solution is evaporated down
  2. additionConcentrated hydrochloric acid is added dropwise to the reaction solution until no more precipitate
  3. customis formed
  4. filtrationThe precipitate is filtered off
  5. washwashed twice with water
  6. customdried

Quellen und Nachweise

ORD-Eintrag
ord-c716151ff7ca41a4ae826ba559d40f79
Quelldatensatz
uspto-grants-2008_04
Patentnummer
US07351719B2

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