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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 901090Erstellt: 25. Oktober 2026

1-Isopropylpiperidin-4-ol → 5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid

https://huagongshe.com/reaction/901090

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt1-Isopropylpiperidin-4-olHCID 79681—
EduktEthyl 5-hydroxy-1H-indole-2-carboxylateHCID 90677—
Edukt5-(1-Isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid ethyl esterHCID 44185246—
Produkt5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acidHCID 59699456—

Reaktionsschritte

According to the procedure described for the synthesis of Example 5/step 1 5-(1-isopropyl-piperidin-4-yloxy)-1H-indole-2-carboxylic acid ethyl ester was synthesized from 5-hydroxy-1H-indole-2-carboxylic acid ethyl ester (commercially available) and 1-isopropyl-piperidin-4-ol (commercially available). The title compound was yielded in 33% as off-white solid. MS (m/e): 331.1 (MH+, 100%).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS07361682B2
Quelldatensatzuspto-grants-2008_04
ORD IDord-3107c198f75b46f3b75c499866bceb56
Quellennotizuspto-grants-2008_04