2-(4-Nitrophenoxy)naphthalene → 2-(4-Aminophenoxy)naphthalene

Beteiligte Stoffe

Reaktionsschritte

The nitro intermediate (10 mmol) obtained above was dissolved in EtOH (50 mL) and hydrogenated in the presence of 10% Pd/C (300 mg) until completion according to General Procedure H, as indicated by TLC or HPLC. The reaction mixture was then filtered to remove the catalyst. The solvent was removed in vacuuo to afford the desired 4-(naphthalen-2-yloxy)aniline, which was used directly for further transformation without further purification.

Herkunft & Nachweise