3-Methyl-2-butenoyl chloride → 2-Hydroxy-5-((3-methylbut-2-enoyl){[2-(4-{[(4-pentylbenzyl)amino]-carbonyl}phenyl)-1,3-thiazol-4-yl]methyl}amino)benzoic acid

Reaktionsgleichung

[CH2:1]([C:6]1[CH:13]=[CH:12][C:9]([CH2:10][NH2:11])=[CH:8][CH:7]=1)[CH2:2][CH2:3][CH2:4][CH3:5].Cl[CH2:15][C:16]1[N:17]=[C:18]([C:21]2[CH:29]=[CH:28][C:24]([C:25](Cl)=[O:26])=[CH:23][CH:22]=2)[S:19][CH:20]=1.[CH3:30][C:31]([CH3:36])=[CH:32][C:33](Cl)=[O:34].[NH2:37][C:38]1[CH:50]=[CH:49][C:41]2[O:42]C(C)(C)[O:44][C:45](=[O:46])[C:40]=2[CH:39]=1>>[OH:42][C:41]1[CH:49]=[CH:50][C:38]([N:37]([C:33](=[O:34])[CH:32]=[C:31]([CH3:36])[CH3:30])[CH2:15][C:16]2[N:17]=[C:18]([C:21]3[CH:29]=[CH:28][C:24]([C:25]([NH:11][CH2:10][C:9]4[CH:12]=[CH:13][C:6]([CH2:1][CH2:2][CH2:3][CH2:4][CH3:5])=[CH:7][CH:8]=4)=[O:26])=[CH:23][CH:22]=3)[S:19][CH:20]=2)=[CH:39][C:40]=1[C:45]([OH:46])=[O:44]