Dimethylamine → [(5-Bromo-2-fluoro-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine
Reaktionsgleichung
[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[Cl-].[Br:12][C:13]1[CH:14]=[CH:15][C:16]([F:23])=[C:17]([CH:22]=1)[CH:18]=[N+:19]([CH3:21])[CH3:20].BrC1C=CC(F)=C(C=1)C=O.CNC>>[Br:12][C:13]1[CH:14]=[CH:15][C:16]([F:23])=[C:17]([CH:18]([N:19]([CH3:20])[CH3:21])[C:4]2[C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[N:2]([CH3:1])[CH:3]=2)[CH:22]=1Komponenten
5
Versuchsvorschrift
The preparation was carried out in accordance with general synthesis instructions 4 from 1-methylindole and (5-bromo-2-fluoro-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 5-bromo-2-fluoro-benzaldehyde and dimethylamine.