Ethylenediamine → HCID 178484971, Verbindung

HRID 903707Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 903707
BrCC1C=CNN=1.C(N)CN.[NH:12]1[CH:16]=[CH:15][C:14]([CH2:17][NH:18][CH2:19][CH2:20][NH2:21])=[N:13]1.[C:22]([NH:24][C:25](=[N:28][CH3:29])SC)#[N:23]>>[C:22]([NH:24][C:25]([NH:28][CH3:29])=[N:21][CH2:20][CH2:19][NH:18][CH2:17][C:14]1[CH:15]=[CH:16][NH:12][N:13]=1)#[N:23]

Komponenten

5

Edukt 4

HCID 3301EthylenediamineHCID 1111031-Cyano-2,3-dimethylisothioureaHCID 1784195145-(Bromomethyl)-1H-pyrazoleHCID 178511340HCID 178511340, Verbindung

Produkt 1

HCID 178484971HCID 178484971, Verbindung

Versuchsvorschrift

Reacting 3-bromomethylpyrazole with ethylenediamine by the procedure of Example 34 and reacting the resulting N-(3-pyrazolylmethyl)ethylenediamine with N-cyano-N',S-dimethylisothiourea by the procedue of Example 3(d) gives N-cyano-N'-methyl-N"-[2-(3-pyrazolylmethylamino)ethyl]guanidine. Hydrolysis of this compound by the procedure of Example 3(e) gives N-methyl-N'-[2-(3-pyrazolylmethylamino)ethyl]-guanidine trihyrochloride.

Quellen und Nachweise

ORD-Eintrag
ord-fef781e7a0d344a28860a28eb26c7659
Quelldatensatz
uspto-grants-1980_10
Patentnummer
US04228291

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