Dimethylamine → [(3-Bromo-phenyl)-(7-ethyl-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9038

Reaktionsgleichung

[CH2:1]([C:3]1[CH:4]=[CH:5][CH:6]=[C:7]2[C:11]=1[NH:10][CH:9]=[CH:8]2)[CH3:2].[Cl-].[Br:13][C:14]1[CH:15]=[C:16]([CH:21]=[CH:22][CH:23]=1)[CH:17]=[N+:18]([CH3:20])[CH3:19].BrC1C=C(C=CC=1)C=O.CNC>>[Br:13][C:14]1[CH:15]=[C:16]([CH:17]([N:18]([CH3:20])[CH3:19])[C:8]2[C:7]3[C:11](=[C:3]([CH2:1][CH3:2])[CH:4]=[CH:5][CH:6]=3)[NH:10][CH:9]=2)[CH:21]=[CH:22][CH:23]=1

Komponenten

Edukt 4

HCID 674Dimethylamine

HCID 765833-Bromobenzaldehyde

HCID 27247117-Ethylindole

HCID 21985337(3-Bromo-benzylidene)-dimethyl-ammonium chloride

Produkt 1

HCID 21985307[(3-Bromo-phenyl)-(7-ethyl-1H-indol-3-yl)-methyl]-dimethyl-amine

Versuchsvorschrift

The preparation was carried out in accordance with general synthesis instructions 4 from 7-ethylindole and (3-bromo-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 3-bromo-benzaldehyde and dimethylamine.

Quellen und Nachweise

ORD-Eintrag: ord-b9dbd5da2cdd4c458aca2c317f2b4bc7
Quelldatensatz: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07091220B2

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