Dimethylamine → [(3-Bromo-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

HRID 9039

Reaktionsgleichung

[CH3:1][N:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH:4]=[CH:3]1.[Cl-].[Br:12][C:13]1[CH:14]=[C:15]([CH:20]=[CH:21][CH:22]=1)[CH:16]=[N+:17]([CH3:19])[CH3:18].BrC1C=C(C=CC=1)C=O.CNC>>[Br:12][C:13]1[CH:14]=[C:15]([CH:16]([N:17]([CH3:19])[CH3:18])[C:4]2[C:5]3[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=3)[N:2]([CH3:1])[CH:3]=2)[CH:20]=[CH:21][CH:22]=1

Komponenten

Edukt 4

HCID 674Dimethylamine

HCID 117811-Methylindole

HCID 765833-Bromobenzaldehyde

HCID 21985337(3-Bromo-benzylidene)-dimethyl-ammonium chloride

Produkt 1

HCID 21985296[(3-Bromo-phenyl)-(1-methyl-1H-indol-3-yl)-methyl]-dimethyl-amine

Versuchsvorschrift

The preparation was carried out in accordance with general synthesis instructions 4 from 1-methylindole and (3-bromo-benzylidene)-dimethyl-ammonium chloride, which had been prepared in accordance with example 24 from 3-bromo-benzaldehyde and dimethylamine.

Quellen und Nachweise

ORD-Eintrag: ord-b13a6bf96a74499cb0f5ac0624c03e7c
Quelldatensatz: uspto-grants-2006_08
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US07091220B2

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