3-Morpholino-2-methyl-1-chloropropane hydrochloride → 4-(3'-Morpholino-2'-methylpropoxy)-3-phenyl-coumarin
Reaktionsgleichung
[OH:1][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[O:5][C:4](=[O:12])[C:3]=1[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.Cl.[O:20]1[CH2:25][CH2:24][N:23]([CH2:26][CH:27]([CH3:30])[CH2:28]Cl)[CH2:22][CH2:21]1>>[O:20]1[CH2:25][CH2:24][N:23]([CH2:26][CH:27]([CH3:30])[CH2:28][O:1][C:2]2[C:11]3[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=3)[O:5][C:4](=[O:12])[C:3]=2[C:13]2[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=2)[CH2:22][CH2:21]1Komponenten
3
Versuchsvorschrift
This compound is prepared according to the method of Example 8 from 14.3 g. (0.06 mol) of 4-hydroxy-3-phenyl-coumarin and 16.7 g. (0.078 mol) of 3-morpholino-2-methyl-1-chloropropane hydrochloride. After recrystallisation from ethanol, 18.8 g. are obtained. Yield 82.5% (theoretical yield 22.8 g.); M.P. 113° C.
Aufarbeitung
- customThis compound is prepared
- customAfter recrystallisation from ethanol, 18.8 g
- custom