HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one → Nabumetone
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 4-(6-Methoxy-2-naphthalenyl)-3-buten-2-one | HCID 53409926 | — |
| Edukt | HCID 178418361 | HCID 178418361 | — |
| Katalysator | Palladium | HCID 23938 | — |
| Lösungsmittel | Ethyl Acetate | HCID 8857 | — |
| Produkt | Nabumetone | HCID 4409 | 69,7% |
Reaktionsschritte
4-(6-Methoxy-2-naphthyl)-3-butene-2-one (32 g) in ethyl acetate (500 ml) was shaken at room temperature over 10% Pd/C (3 g) under atmospheric pressure hydrogen until no further uptake of hydrogen occurred to yield 4-(6-methoxy-2-naphthyl)butan-2-one (22.5 g), mp. 78.5° C.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04420639 |
| Quelldatensatz | uspto-grants-1983_12 |
| ORD ID | ord-2d41f0e4ef95449290297d6d08cfd8ca |
| Quellennotiz | uspto-grants-1983_12 |