6-Bromo-4-methylisoquinolin-1(2H)-one → 4-Methyl-3-(4-methyl-1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzoic acid, methyl ester

HRID 907322Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 907322
[CH3:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[C:18](=[O:22])[NH:17][CH:16]=[CH:15]2.Br[C:24]1C=C2C(=CC=1)C(=O)NC=C2C>>[CH3:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][C:3]=1[C:12]1[CH:13]=[C:14]2[C:19](=[CH:20][CH:21]=1)[C:18](=[O:22])[NH:17][CH:16]=[C:15]2[CH3:24]

Komponenten

3

Edukt 2

HCID 574398986-Bromo-4-methylisoquinolin-1(2H)-oneHCID 575518084-Methyl-3-(1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzoic acid, methyl ester

Produkt 1

HCID 575517644-Methyl-3-(4-methyl-1-oxo-1,2-dihydro-isoquinolin-6-yl)-benzoic acid, methyl ester

Versuchsvorschrift

The sub-title compound was prepared by the method of intermediate 3 using the product of step i).

Quellen und Nachweise

ORD-Eintrag
ord-608b8e06374042c4a0a79b455913ac0c
Quelldatensatz
uspto-grants-2011_09
Patentnummer
US08012979B2

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