HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
[1-(Cyclopropylcarbamoylhydroxymethyl)cyclopropyl]carbamic acid tert-butyl ester → 2-(1-aminocyclopropyl)-N-cyclopropyl-2-hydroxyacetamide
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | [1-(Cyclopropylcarbamoylhydroxymethyl)cyclopropyl]carbamic acid tert-butyl ester | HCID 67385903 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Lösungsmittel | Trifluoroacetic acid | HCID 6422 | — |
| Produkt | 2-(1-aminocyclopropyl)-N-cyclopropyl-2-hydroxyacetamide | HCID 57562096 | — |
Reaktionsschritte
A solution of [1-(cyclopropylcarbamoylhydroxymethyl)cyclopropyl]carbamic acid tert-butyl ester in CH2Cl2 (5 mL) and TFA (5 mL) was stirred at room temperature for 2.5 h. The reaction mixture was concentrated and chased with toluene to yield 2-(1-aminocyclopropyl)-N-cyclopropyl-2-hydroxyacetamide.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08013183B2 |
| Quelldatensatz | uspto-grants-2011_09 |
| ORD ID | ord-52f96089a75549af8ac930f20452d90b |
| Quellennotiz | uspto-grants-2011_09 |