Chlorotrimethylsilane → 2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-[3-(1H-indol-3-yl)propyl]acetamide hydrochloride

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Reaktionsschritte

2-(4-Dimethylamino-4-phenylcyclohexylidene)-N-[3-(1H-indol-3-yl)propyl]acetamide (742 mg, 1.78 mmol) was dissolved in ethyl methyl ketone (25 ml), and chlorotrimethylsilane (0.34 ml, 2.7 mmol) was added. After 2 h the hydrochloride was isolated as a beige-coloured solid with an m.p. of 165-173° C. in a yield of 75% (606 mg).

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