BROMINE CHLORIDE (BrCl) → HCID 178421697, Verbindung

Beteiligte Stoffe

Reaktionsschritte

From 3-bromo-5-tert-butyl-6-hydroxy-2-methyl-benzoic acid phenyl ester and 2-amino-4-chlorobenzenesulfonamide; obtained as white crystals following column chromatography (silica gel/EtOAc-heptane-CH2Cl2 1:6:3); mp 270-271° C. (decomp., ebullition); 1H NMR (DMSO): δ 12.58 (s, 1H, NH), 9.64 (s, 1H), 7.91 (d, J=8.3 Hz, 1H), 7.55 (dd, J˜8.3, 1.9 Hz, 1H), 7.48 (s, 1H), 7.34 (d, J=1.9 Hz, 1H), 2.20 (s, 3H), 1.37 (s, 9H); LC-MS: m/z 457/459/461 (M+H; BrCl isotope pattern), 935/937/939/941 (2M+Na; Br2Cl2 isotope pattern); Rt=2.24 min.

Herkunft & Nachweise