Methyl 2-(3-phenoxypropenyl)benzoate → Methyl 2-(3-phenoxypropyl)benzoate

HRID 910166Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 910166
[O:1]([CH2:8][CH:9]=[CH:10][C:11]1[CH:20]=[CH:19][CH:18]=[CH:17][C:12]=1[C:13]([O:15][CH3:16])=[O:14])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO.[C].[Pd]>[O:1]([CH2:8][CH2:9][CH2:10][C:11]1[CH:20]=[CH:19][CH:18]=[CH:17][C:12]=1[C:13]([O:15][CH3:16])=[O:14])[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Komponenten

4

Edukt 1

HCID 67414986Methyl 2-(3-phenoxypropenyl)benzoate

Produkt 1

HCID 67413057Methyl 2-(3-phenoxypropyl)benzoateAusbeute 55 %

Reagenzien, Katalysatoren, Lösungsmittel 2

HCID 178418390HCID 178418390, VerbindungKatalysatorHCID 887MethanolLösungsmittel

Versuchsvorschrift

The thus-obtained methyl 2-(3-phenoxypropenyl)benzoate (0.261 g, 0.972 mmol) was dissolved in methanol (6 ml), 10% palladium carbon (0.022 g) was added, and a hydrogenation reaction was performed at room temperature for 24 hr. The reaction mixture was filtered through celite, the filtrate was concentrated under reduced pressure, and the obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate) to give methyl 2-(3-phenoxypropyl)benzoate (0.144 g, 0.533 mmol, yield 55%).

Aufarbeitung

  1. customa hydrogenation reaction
  2. filtrationThe reaction mixture was filtered through celite
  3. concentrationthe filtrate was concentrated under reduced pressure
  4. customthe obtained residue was purified by silica gel column chromatography (hexane:ethyl acetate)

Quellen und Nachweise

ORD-Eintrag
ord-81897f41f7554283830d72136a92baea
Quelldatensatz
uspto-grants-2011_09
Patentnummer
US08022072B2

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