Ammonia → N-p-Bromophenylthiourea

HRID 910227

Reaktionsgleichung

Reaktionsgleichung von HRID 910227
[Br:1][C:2]1[CH:7]=[CH:6][C:5]([N:8]=[C:9]=[S:10])=[CH:4][CH:3]=1.[NH3:11]>O1CCCC1>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][C:9]([NH2:11])=[S:10])=[CH:4][CH:3]=1

Komponenten

4

Edukt 2

HCID 222AmmoniaHCID 161334-Bromophenyl isothiocyanate

Produkt 1

HCID 2735620N-p-Bromophenylthiourea

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 8028TetrahydrofuranLösungsmittel

Versuchsvorschrift

4-Bromophenylisothiocyanate (21.4 g) was dissolved in tetrahydrofuran (50 mL), and concentrated aqueous ammonia (28%) (13.7 mL) was added dropwise to the solution, followed by stirring at room temperature for 10 minutes. The solvent was concentrated under reduced pressure, and the crystals were recovered through filtration by use of water, followed by recrystallization from ethanol, to thereby yield the title compound (16.4 g).

Aufarbeitung

  1. concentrationThe solvent was concentrated under reduced pressure
  2. filtrationthe crystals were recovered through filtration by use of water
  3. customfollowed by recrystallization from ethanol

Quellen und Nachweise

ORD-Eintrag
ord-21dc0986b22b4059a3b8ea7a202da54c
Quelldatensatz
uspto-grants-2011_09
Patentnummer
US08022075B2

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