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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 910233Erstellt: 24. Oktober 2026

Water → 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole

https://huagongshe.com/de/reaction/910233

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
EduktWaterHCID 962—
Edukt2-Amino-5-bromobenzene-1-thiolHCID 1209045—
Edukt4-(5-Oxazolyl)benzaldehydeHCID 10583346—
LösungsmittelDimethyl SulfoxideHCID 679—
Produkt5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazoleHCID 6740528758,8%

Reaktionsbedingungen

Temperatur160 °C

Reaktionsschritte

2 Amino-5-bromobenzenethiol (102 mg) and 4-(1,3-oxazol-5-yl)benzaldehyde (87 mg) were dissolved in dimethylsulfoxide (1 mL), followed by stirring at 160° C. for 10 minutes. Water (10 mL) was added to the reaction mixture. The precipitated matter was recovered through filtration, and washed with methanol, to thereby yield the title compound (105 mg).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS08022075B2
Quelldatensatzuspto-grants-2011_09
ORD IDord-0e754375d48d4d6aa7a3d6b803037183
Quellennotizuspto-grants-2011_09