HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Water → 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Water | HCID 962 | — |
| Edukt | 2-Amino-5-bromobenzene-1-thiol | HCID 1209045 | — |
| Edukt | 4-(5-Oxazolyl)benzaldehyde | HCID 10583346 | — |
| Lösungsmittel | Dimethyl Sulfoxide | HCID 679 | — |
| Produkt | 5-[4-(6-Bromo-1,3-benzothiazol-2-yl)phenyl]-1,3-oxazole | HCID 67405287 | 58,8% |
Reaktionsbedingungen
| Temperatur | 160 °C |
|---|
Reaktionsschritte
2 Amino-5-bromobenzenethiol (102 mg) and 4-(1,3-oxazol-5-yl)benzaldehyde (87 mg) were dissolved in dimethylsulfoxide (1 mL), followed by stirring at 160° C. for 10 minutes. Water (10 mL) was added to the reaction mixture. The precipitated matter was recovered through filtration, and washed with methanol, to thereby yield the title compound (105 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08022075B2 |
| Quelldatensatz | uspto-grants-2011_09 |
| ORD ID | ord-0e754375d48d4d6aa7a3d6b803037183 |
| Quellennotiz | uspto-grants-2011_09 |