Potassium Phosphate, Tribasic → HCID 24826661, Verbindung

Beteiligte Stoffe

Reaktionsschritte

Using the method of Example 3, Step B, 4-methylthiazol-2-amine (0.244 g, 2.14 mmol), 2-chloro-4-(2,6-dimethylphenoxy)pyridine (0.500 g, 2.14 mmol), potassium phosphate (0.500 g, 2.35 mmol), Pd2(dba)3 (0.098 g, 0.107 mmol), and 4,5-bis(diphenylphosphino)-9,9-dimethyl-9H-xanthene (0.062 g, 0.107 mmol) were reacted to provide N-(4-(2,6-dimethylphenoxy)pyridin-2-yl)-4-methylthiazol-2-amine (0.290 g, 44% yield). 1H NMR (d6-DMSO) δ 10.93 (s, 1H), 8.13 (d, 1H), 7.15-7.22 (m, 3H), 6.50 (s, 1H), 6.40 (d, 1H), 6.39 (s, 1H), 2.19 (s, 3H), 2.08 (s, 6H).

Herkunft & Nachweise