1-Iodo-4-nitrobenzene → N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	1-Iodo-4-nitrobenzene	HCID 12495	—
Edukt	1-(3-Aminopropyl)-4-methylpiperazine	HCID 78328	—
Produkt	N-[3-(4-methylpiperazin-1-yl)propyl]-4-nitro-1-aminobenzene	HCID 21975010	—

Reaktionsschritte

Using 1-iodo-4-nitro-benzene (500 mg) instead of 1-bromo-3-nitro-benzene, and 3-(4-methyl-piperazin-1-yl)-propylamine (379 mg) instead of morpholine, in the same manner as Step A in Example 1-D-105, the desired compound was obtained (432 mg, 77%).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08022205B2
Quelldatensatz	uspto-grants-2011_09
ORD ID	ord-e4660a3f5af040859863afab87d5fd01
Quellennotiz	uspto-grants-2011_09