HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Allyl bromide → 3-Allyloxy-4-methoxybenzaldehyde
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Allyl bromide | HCID 7841 | — |
| Edukt | Potassium Carbonate | HCID 11430 | — |
| Edukt | Isovanillin | HCID 12127 | — |
| Edukt | 3-Ethoxy-4-methylbenzaldehyde | HCID 25242058 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 3-Allyloxy-4-methoxybenzaldehyde | HCID 534148 | — |
Reaktionsschritte
The title compound was prepared analogously to 3-ethoxy-4-methyl-benzaldehyde (intermediate E10) by reaction of 3-hydroxy-4-methoxy-benzaldehyde with allylbromide in DMF using K2CO3 as base (see also A. W. White, R. Almassy, A. H. Calvert, N. J. Curtin, R. J. Griffin, Z. Hostomsky, K. Maegley, D. R. Newell, S. Srinivasan and B. T. Golding J. Med. Chem. 2000, 43, 4084-4097).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US08026255B2 |
| Quelldatensatz | uspto-grants-2011_09 |
| ORD ID | ord-9b2a613a32ef49a39cfc5cedf03cc61e |
| Quellennotiz | uspto-grants-2011_09 |