5-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole → 1-({5-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	5-[3,5-Bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole	HCID 2780957	—
Edukt	4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile	HCID 24985632	—
Produkt	1-({5-[3,5-Bis(trifluoromethyl)phenyl]-1,2,4-oxadiazol-3-yl}methyl)-4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile	HCID 24985968	—

Reaktionsschritte

Synthesized as described in Example 39 from 4-chloro-2-(difluoromethyl)-1H-indole-5-carbonitrile and 5-[3,5-bis(trifluoromethyl)phenyl]-3-(chloromethyl)-1,2,4-oxadiazole: MS (ESI) m/z 519 (M−1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08026262B2
Quelldatensatz	uspto-grants-2011_09
ORD ID	ord-855a89b53aaf4eb3b3ed296256c75e1f
Quellennotiz	uspto-grants-2011_09