3-Bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine → 1-{[5-(5-Bromo-3-pyridinyl)-1,3,4-oxadiazol-2-yl]methyl}-2-propyl-1H-indole-4,5-dicarbonitrile

Beteiligte Stoffe

Reaktionsschritte

Synthesized as described in Example 4 from 2-propyl-1H-indole-4,5-dicarbonitrile and 3-bromo-5-[5-(chloromethyl)-1,3,4-oxadiazol-2-yl]pyridine: 1H NMR (400 MHz, DMSO-d6) δ 9.05 (d, J=1.7 Hz, 1 H), 8.95 (d, J=2.1 Hz, 1 H), 8.48 (s, 1 H), 8.16 (s, 1 H), 7.91 (d, J=8.7 Hz, 1 H), 7.57 (d, J=8.7 Hz, 1 H), 6.05 (s, 2 H), 3.07 (t, J=7.6 Hz, 2 H), 1.78-1.67 (m, 2 H), 0.96 (t, J=7.6 Hz, 3 H); MS (ES) m/z 448 (M+1).

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