3,5-Bis-trifluoromethylphenylboronic acid → 1-{[3',5'-bis(Trifluoromethyl)-3-biphenylyl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile

Beteiligte Stoffe

Rolle	Name	HCID	Einwaage
Edukt	3,5-Bis-trifluoromethylphenylboronic acid	HCID 156265	—
Edukt	1-[(3-Bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 67405035	—
Produkt	1-{[3',5'-bis(Trifluoromethyl)-3-biphenylyl]methyl}-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile	HCID 86620704	—

Reaktionsschritte

Synthesized as described in Example 310D using 1-[(3-bromophenyl)methyl]-2-methyl-4-(trifluoromethyl)-1H-indole-5-carbonitrile (Example 318A) and [3,5-bis(trifluoromethyl)phenyl]boronic acid: MS (ES) m/z 527 (M+1).

Herkunft & Nachweise

DOI	10.6084/m9.figshare.5104873.v1
Patentnummer	US08026262B2
Quelldatensatz	uspto-grants-2011_09
ORD ID	ord-07284c2369c844638e1d5a79c921c88e
Quellennotiz	uspto-grants-2011_09