tert-Butyl 2-bromobutanoate → HCID 67396891, Verbindung
Reaktionsgleichung
[CH2:1]([O:3][C:4](=[O:12])[CH2:5][C:6]1[N:7]=[C:8]([SH:11])[S:9][CH:10]=1)[CH3:2].[C:13]([O:17][C:18](=[O:23])[CH:19](Br)[CH2:20][CH3:21])([CH3:16])([CH3:15])[CH3:14]>>[C:13]([O:17][C:18](=[O:23])[CH:19]([S:11][C:8]1[S:9][CH:10]=[C:6]([CH2:5][C:4]([O:3][CH2:1][CH3:2])=[O:12])[N:7]=1)[CH2:20][CH3:21])([CH3:16])([CH3:15])[CH3:14]Komponenten
3
Versuchsvorschrift
The title compound was obtained by an operation similar to that of Example 2 and using (2-mercapto-1,3-thiazol-4-yl)acetic acid ethyl ester synthesized in Example 1 and 2-bromobutanoic acid tert-butyl ester to give 2-{[4-(2-ethoxy-2-oxoethyl)-1,3-thiazol-2-yl]thio}butanoic acid tert-butyl ester, followed by operations similar to those of Examples 3, 4 and 34.
Quellen und Nachweise
- ORD-Eintrag
- ord-00b45bea73834f159896c477ae6abad8
- Quelldatensatz
- uspto-grants-2011_09