HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
N,N,N',N'-Tetramethylazodicarboxamide → HCID 69280251, Verbindung
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | N,N,N',N'-Tetramethylazodicarboxamide | HCID 4278 | — |
| Edukt | Tributylphosphine | HCID 13831 | — |
| Edukt | {1-methyl-3-[4-(trifluoromethoxy)phenyl]-1H-pyrazol-5-yl}methanol | HCID 44818672 | — |
| Edukt | (5-Hydroxy-indol-1-yl)-acetic acid ethyl ester | HCID 57675474 | — |
| Produkt | HCID 69280251 | HCID 69280251 | — |
Reaktionsschritte
In analogy to the procedure described for example 3 c], (5-hydroxy-indol-1-yl)-acetic acid ethyl ester was reacted with [2-methyl-5-(4-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-methanol in the presence of N,N,N′,N′-tetramethyl azodicarboxamide and tributylphosphine to give {5-[2-methyl-5-(4-trifluoromethoxy-phenyl)-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid ethyl ester as colorless oil.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07265149B2 |
| Quelldatensatz | uspto-grants-2007_09 |
| ORD ID | ord-00e4af02a7274c748801f46f7377dae3 |
| Quellennotiz | uspto-grants-2007_09 |