2,2,2-Trifluoroethyl trifluoromethanesulfonate → 2-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester

HRID 915448Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 915448
[CH2:1]([O:3][C:4]([C:6]1[CH:10]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][C:18]([F:21])([F:20])[F:19])=[CH:13][CH:12]=2)[NH:8][N:7]=1)=[O:5])[CH3:2].[F:22][C:23]([F:34])([F:33])[CH2:24]OS(C(F)(F)F)(=O)=O>>[CH2:1]([O:3][C:4]([C:6]1[N:7]([CH2:24][C:23]([F:34])([F:33])[F:22])[N:8]=[C:9]([C:11]2[CH:16]=[CH:15][C:14]([O:17][C:18]([F:21])([F:20])[F:19])=[CH:13][CH:12]=2)[CH:10]=1)=[O:5])[CH3:2]

Komponenten

3

Edukt 2

HCID 803662,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 178468641HCID 178468641, Verbindung

Produkt 1

HCID 866006282-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester

Versuchsvorschrift

In analogy to the procedure described for example 13 a], 5-(4-trifluoromethoxy-phenyl)-1H-pyrazole-3-carboxylic acid ethyl ester (example 11 b]) was reacted with trifluoroethyltriflate to give 2-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazole-3-carboxylic acid ethyl ester as colorless solid.

Quellen und Nachweise

ORD-Eintrag
ord-b7fea0c673284251a1ee5388d78f7629
Quelldatensatz
uspto-grants-2007_09
Patentnummer
US07265149B2

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