Ethyl isocyanate → 1-(6-Bromo-2-benzothiazolyl)-3-ethylurea

Beteiligte Stoffe

Reaktionsbedingungen

Reaktionsschritte

About 0.75 g of 6-bromo-1,3-benzothiazol-2-amine (crude) is dissolved in about 15 mL DMF. About 0.5 mL of ethylisocyanate is added followed by about 0.9 mL triethylamine and the solution is heated to about 80° C. under good agitation. The solution is allowed to stir for about 4 hours then cooled to RT. The solvent is removed in vacuo and the solids are washed well with ether. The product is further purified by column chromatography.

Herkunft & Nachweise