Phenol → [(1R,5S)-5-Hydroxycyclopent-2-en-1-yl]acetic acid

Reaktionsgleichung

[C:1]1([OH:7])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[C:8]([O-])([O-:13])([O:10]CC)C>>[OH:7][C@H:1]1[CH2:6][CH:5]=[CH:4][C@H:3]1[CH2:2][C:8]([OH:13])=[O:10]

Komponenten

Edukt 2

HCID 996Phenol

HCID 86598186Ethyl ortho-acetate

Produkt 1

HCID 12813247[(1R,5S)-5-Hydroxycyclopent-2-en-1-yl]acetic acid

Versuchsvorschrift

In the same manner as described in Example 1 but using 0.5 part of phenol in place of the hydroquinone, 7 parts of unreacted ethyl orthoacetate was recovered and then 4.2 parts of the desired product, a lactone of cis-2-hydroxy-cyclopent-4-ene-1-acetic acid was obtained.

Aufarbeitung

customwas recovered

Quellen und Nachweise

ORD-Eintrag: ord-36670f1655184ab0bbbbec30f7e23d1f
Quelldatensatz: uspto-grants-1976_07
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US03970673

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