4-(Trifluoromethoxy)aniline → 6-Bromo-N-(4-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918822

Reaktionsgleichung

Reaktionsgleichung von HRID 918822
[F:1][C:2]([F:12])([F:11])[O:3][C:4]1[CH:10]=[CH:9][C:7]([NH2:8])=[CH:6][CH:5]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23](OCC)=[O:24])[N:22]=2)[CH:19]=1>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23]([NH:8][C:7]3[CH:9]=[CH:10][C:4]([O:3][C:2]([F:11])([F:12])[F:1])=[CH:5][CH:6]=3)=[O:24])[N:22]=2)[CH:19]=1

Komponenten

3

Edukt 2

HCID 6008484-(Trifluoromethoxy)anilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Produkt 1

HCID 1181139336-Bromo-N-(4-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

Versuchsvorschrift

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 4-(trifluoromethoxy)aniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Quellen und Nachweise

ORD-Eintrag
ord-6f3836246ec94f7d89de56932a4618e3
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09271969B2

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