4-(Trifluoromethyl)benzylamine → 6-Bromo-N-(4-(trifluoromethyl)benzyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918823

Reaktionsgleichung

Reaktionsgleichung von HRID 918823
[F:1][C:2]([F:12])([F:11])[C:3]1[CH:8]=[CH:7][C:6]([CH2:9][NH2:10])=[CH:5][CH:4]=1.[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23](OCC)=[O:24])[N:22]=2)[CH:19]=1>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23]([NH:10][CH2:9][C:6]3[CH:5]=[CH:4][C:3]([C:2]([F:11])([F:12])[F:1])=[CH:8][CH:7]=3)=[O:24])[N:22]=2)[CH:19]=1

Komponenten

3

Edukt 2

HCID 768044-(Trifluoromethyl)benzylamineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Produkt 1

HCID 1181139946-Bromo-N-(4-(trifluoromethyl)benzyl)imidazo[1,2-a]pyridine-2-carboxamide

Versuchsvorschrift

The title compound was prepared by essentially following the same procedures described for Intermediate I, using (4-(trifluoromethyl)phenyl)methanamine and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Quellen und Nachweise

ORD-Eintrag
ord-53dee3be28f0413aa906be3bf2ddb49d
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09271969B2

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