3-(Trifluoromethoxy)aniline → 6-Bromo-N-(3-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

HRID 918824

Reaktionsgleichung

Reaktionsgleichung von HRID 918824
[F:1][C:2]([F:12])([F:11])[O:3][C:4]1[CH:5]=[C:6]([CH:8]=[CH:9][CH:10]=1)[NH2:7].[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23](OCC)=[O:24])[N:22]=2)[CH:19]=1>>[Br:13][C:14]1[CH:15]=[CH:16][C:17]2[N:18]([CH:20]=[C:21]([C:23]([NH:7][C:6]3[CH:8]=[CH:9][CH:10]=[C:4]([O:3][C:2]([F:11])([F:12])[F:1])[CH:5]=3)=[O:24])[N:22]=2)[CH:19]=1

Komponenten

3

Edukt 2

HCID 737533-(Trifluoromethoxy)anilineHCID 7141939Ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate

Produkt 1

HCID 897417926-Bromo-N-(3-(trifluoromethoxy)phenyl)imidazo[1,2-a]pyridine-2-carboxamide

Versuchsvorschrift

The title compound was prepared by essentially following the same procedures described for Intermediate I, using 3-(trifluoromethoxy)aniline and ethyl 6-bromoimidazo[1,2-a]pyridine-2-carboxylate as starting materials.

Quellen und Nachweise

ORD-Eintrag
ord-f0519d74b8b44097a2d813d0a89f2df9
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09271969B2

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