2-Chloro-6-fluorobenzylamine → 2-bromo-N-(2-chloro-6-fluorobenzyl)imidazo[2,1-b]thiazole-6-carboxamide

HRID 918880

Reaktionsgleichung

Reaktionsgleichung von HRID 918880
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([F:8])[C:3]=1[CH2:9][NH2:10].[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20](O)=[O:21])=[CH:19][N:14]2[CH:13]=1>>[Br:11][C:12]1[S:16][C:15]2=[N:17][C:18]([C:20]([NH:10][CH2:9][C:3]3[C:4]([F:8])=[CH:5][CH:6]=[CH:7][C:2]=3[Cl:1])=[O:21])=[CH:19][N:14]2[CH:13]=1

Komponenten

3

Edukt 2

HCID 848332-Chloro-6-fluorobenzylamineHCID 127446152-Bromoimidazo[2,1-b]thiazole-6-carboxylic acid

Produkt 1

HCID 1181139242-bromo-N-(2-chloro-6-fluorobenzyl)imidazo[2,1-b]thiazole-6-carboxamide

Versuchsvorschrift

The title compound was prepared by essentially following the same procedures described for Intermediate XLIV, using (2-chloro-6-fluorophenyl)methanamine and 2-bromoimidazo[2,1-b]thiazole-6-carboxylic acid as starting materials.

Quellen und Nachweise

ORD-Eintrag
ord-1bc04b8e182e4c43a495259eb839df50
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09271969B2

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