Sodium Hydroxide → HCID 178506294, Verbindung

Reaktionsgleichung

P(Cl)(Cl)([Cl:3])=O.[F:6][C:7]([F:19])([F:18])[C:8]1[C:16]2[C:11](=[N+:12]([O-])[CH:13]=[CH:14][CH:15]=2)[NH:10][N:9]=1.[OH-].[Na+]>>[Cl:3][C:15]1[CH:14]=[CH:13][N:12]=[C:11]2[NH:10][N:9]=[C:8]([C:7]([F:19])([F:18])[F:6])[C:16]=12

Komponenten

Edukt 3

HCID 14798Sodium Hydroxide

HCID 24813Phosphorus oxychloride

HCID 178526242HCID 178526242, Verbindung

Produkt 1

HCID 178506294HCID 178506294, VerbindungAusbeute 27 %

Reaktionsbedingungen

Temperatur: 100 °C

Versuchsvorschrift

Phosphorus oxychloride (76.4 g) was gradually added to compound (1b) (33.2 g), followed by stirring at 100° C. for 1 hr. The reaction solution was poured into ice water, and sodium hydroxide was added thereto to adjust the pH to 10. The precipitate was collected by filtration to obtain compound (1c) (9.76 g, 270) as a light pink solid.