HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
hydrogen chloride CPME → N-[4-(trans-2-aminocyclopropyl)-2-methylphenyl]benzamide hydrochloride
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | hydrogen chloride CPME | HCID 66926893 | — |
| Edukt | tert-Butyl {trans-2-[4-(benzoylamino)-3-methylphenyl]cyclopropyl}carbamate | HCID 86729917 | — |
| Produkt | N-[4-(trans-2-aminocyclopropyl)-2-methylphenyl]benzamide hydrochloride | HCID 86729915 | — |
Reaktionsschritte
tert-Butyl {trans-2-[4-(benzoylamino)-3-methylphenyl]cyclopropyl}carbamate (125.8 mg) was dissolved in 4N hydrochloric acid/cyclopentyl methyl ether solution (1.5 mL), and the mixture was stirred at room temperature for 2 hr. The solvent was evaporated under reduced pressure to give the title compound (95.9 mg).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09278931B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-b95ec5a89708440e9cc9ff1fdf103d08 |
| Quellennotiz | uspto-grants-2016_03 |