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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 922548Erstellt: 25. Oktober 2026

hydrogen chloride CPME → N-[4-(trans-2-aminocyclopropyl)-2-methylphenyl]benzamide hydrochloride

https://huagongshe.com/reaction/922548

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukthydrogen chloride CPMEHCID 66926893—
Edukttert-Butyl {trans-2-[4-(benzoylamino)-3-methylphenyl]cyclopropyl}carbamateHCID 86729917—
ProduktN-[4-(trans-2-aminocyclopropyl)-2-methylphenyl]benzamide hydrochlorideHCID 86729915—

Reaktionsschritte

tert-Butyl {trans-2-[4-(benzoylamino)-3-methylphenyl]cyclopropyl}carbamate (125.8 mg) was dissolved in 4N hydrochloric acid/cyclopentyl methyl ether solution (1.5 mL), and the mixture was stirred at room temperature for 2 hr. The solvent was evaporated under reduced pressure to give the title compound (95.9 mg).

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09278931B2
Quelldatensatzuspto-grants-2016_03
ORD IDord-b95ec5a89708440e9cc9ff1fdf103d08
Quellennotizuspto-grants-2016_03