Trifluoroacetic acid → (S)-3,3-dimethyl-2-(((S)-tetrahydrofuran-3-yloxy)carbonylamino)butanoic acid
Reaktionsgleichung
[CH3:1][C:2]([CH3:21])([CH3:20])[C@H:3]([NH:11][C:12]([O:14][C@H:15]1[CH2:19][CH2:18][O:17][CH2:16]1)=[O:13])[C:4]([O:6]C(C)(C)C)=[O:5].FC(F)(F)C(O)=O>ClCCl>[CH3:1][C:2]([CH3:21])([CH3:20])[C@H:3]([NH:11][C:12]([O:14][C@H:15]1[CH2:19][CH2:18][O:17][CH2:16]1)=[O:13])[C:4]([OH:6])=[O:5]Komponenten
4
Edukt 2
Produkt 1
Reagenzien, Katalysatoren, Lösungsmittel 1
Versuchsvorschrift
To a solution of the product from Example 59A (0.037 g, 0.123 mmol) in dichloromethane (1.2 mL) was added trifluoroacetic acid (1.2 mL) and the mixture was stirred at room temperature for 2 hours. The solvent was evaporated to give the title compound which was used without further purification.