5-Bromo-6-chloropyridine-3-carboxylic acid → HCID 89907270, Verbindung
Reaktionsgleichung
[Br:1][C:2]1[C:3]([Cl:11])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([OH:9])=O.[F:12][C:13]([F:25])([O:17][C:18]1[CH:24]=[CH:23][C:21]([NH2:22])=[CH:20][CH:19]=1)[CH:14]([F:16])[F:15]>>[Br:1][C:2]1[C:3]([Cl:11])=[N:4][CH:5]=[C:6]([CH:10]=1)[C:7]([NH:22][C:21]1[CH:20]=[CH:19][C:18]([O:17][C:13]([F:12])([F:25])[CH:14]([F:15])[F:16])=[CH:24][CH:23]=1)=[O:9]Komponenten
3
Versuchsvorschrift
The title compound was prepared in an analogous fashion to that described in Stage 169.2 using 5-bromo-6-chloro-nicotinic acid and 4-(1,1,2,2-tetrafluoroethoxy)aniline to afford a solid. UPLC-MS (Condition 3), tR=1.2 min, m/z=424.9 [M+H]+.
Aufarbeitung
- customto afford a solid
Quellen und Nachweise
- ORD-Eintrag
- ord-9f0f7ac28ec04da8ad5f555499c13bf1
- Quelldatensatz
- uspto-grants-2016_03