4-Hydroxyphenylsulfur pentafluoride → 4-Methoxy-4'-(pentafluorosulfanyl)biphenyl

HRID 926108

Reaktionsgleichung

Reaktionsgleichung von HRID 926108
F[B-](F)(F)F.[F:6][S:7]([F:19])([F:18])([F:17])([F:16])[C:8]1[CH:13]=[CH:12][C:11]([N+]#N)=[CH:10][CH:9]=1.FC1C=CC(S(F)(F)(F)(F)F)=CC=1.[CH3:33][O:34][C:35]1[CH:40]=[CH:39][C:38](S(F)(F)(F)(F)F)=[CH:37][CH:36]=1.FS(F)(F)(F)(F)C1C=CC(O)=CC=1>CO>[CH3:33][O:34][C:35]1[CH:40]=[CH:39][C:38]([C:11]2[CH:12]=[CH:13][C:8]([S:7]([F:19])([F:18])([F:17])([F:16])[F:6])=[CH:9][CH:10]=2)=[CH:37][CH:36]=1

Komponenten

6

Edukt 4

HCID 27792034-Hydroxyphenylsulfur pentafluorideHCID 232332104-Fluorophenylsulfur PentafluorideHCID 596421411-Methoxy-4-(pentafluoro-lambda~6~-sulfanyl)benzeneHCID 1222352751605274-62-1

Produkt 1

HCID 1186563654-Methoxy-4'-(pentafluorosulfanyl)biphenyl

Reagenzien, Katalysatoren, Lösungsmittel 1

HCID 887MethanolLösungsmittel2×

Versuchsvorschrift

In Methanol: Diazonium salt 1 (22.5 mg, 0.0314 mmol) was dissolved in methanol (0.82 mL). After 13 d stirring at room temp. a portion of the solution was diluted with CDCl3 and analyzed by NMR, which indicated the formation of 1-fluoro-4-(pentafluorosulfanyl)benzene 30, (Umemoto, et al., Beilstein J. Org. Chem. 2012, 8, 461-471) 1-methoxy-4-(pentafluorosulfanyl)-benzene, (Beier, et al., Org. Lett. 2011, 13, 1466-1469) and 4-(pentafluorosulfanyl)phenol (Beier, et al., Org. Lett. 2011, 13, 1466-1469).

Aufarbeitung

  1. additionwas diluted with CDCl3

Quellen und Nachweise

ORD-Eintrag
ord-b7ca4a24287e4a81890444dfcc691de8
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09284336B1

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