HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide → N-methacryloylglycylglycyl-thiazolidine-2-thione
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1-Ethyl-3-(3'-dimethylaminopropyl)carbodiimide | HCID 15908 | — |
| Edukt | Methacryloylglycylglycine | HCID 10241886 | — |
| Edukt | HCID 178527880 | HCID 178527880 | — |
| Katalysator | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Lösungsmittel | Dichloromethane | HCID 6344 | — |
| Produkt | N-methacryloylglycylglycyl-thiazolidine-2-thione | HCID 58455605 | — |
Reaktionsschritte
The synthesis of MA-GG-TT was similar to the synthesis of MA-GFLG-TT in Example 1. N-methacryloylglycylglycine (MA-GG-OH) was coupled with 2-mercaptothiazoline in DCM mediated by EDCI in presence of catalytic amount of DMAP. After reaction, the product was purified by recrystallization from MeOH solution.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09289510B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-7570d324d8d74bb897fc76c6c33cdc28 |
| Quellennotiz | uspto-grants-2016_03 |