2-(1,2,4-Oxadiazol-3-yl)propan-2-amine → 6-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amide

HRID 927537Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 927537
[CH:1]1([CH2:4][O:5][C:6]2[N:11]=[C:10]([C:12]([OH:14])=O)[CH:9]=[CH:8][C:7]=2[C:15]([F:18])([F:17])[F:16])[CH2:3][CH2:2]1.[CH3:19][C:20]([NH2:27])([C:22]1[N:26]=[CH:25][O:24][N:23]=1)[CH3:21]>>[CH3:19][C:20]([NH:27][C:12]([C:10]1[CH:9]=[CH:8][C:7]([C:15]([F:18])([F:17])[F:16])=[C:6]([O:5][CH2:4][CH:1]2[CH2:2][CH2:3]2)[N:11]=1)=[O:14])([C:22]1[N:26]=[CH:25][O:24][N:23]=1)[CH3:21]

Komponenten

3

Edukt 2

HCID 435591182-(1,2,4-Oxadiazol-3-yl)propan-2-amineHCID 710874576-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid

Produkt 1

HCID 711056076-Cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (1-methyl-1-[1,2,4]oxadiazol-3-yl-ethyl)-amide

Versuchsvorschrift

The title compound was synthesized in analogy to Example 1, using 6-cyclopropylmethoxy-5-trifluoromethyl-pyridine-2-carboxylic acid (Example 113 d) and 1-methyl-1-[1,2,4]oxadiazol-3-yl ethylamine (CAN 1153757-41-5) as starting materials, MS (EI): m/e=371.2 [M+H]+.

Quellen und Nachweise

ORD-Eintrag
ord-83660315cbfa45af9be268187960e9e3
Quelldatensatz
uspto-grants-2016_03
Patentnummer
US09290451B2

Notizen zur Reaktion

Wird geladen…