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HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
HRID 927747Erstellt: 25. Oktober 2026

(2S)-2-Amino-2-phenylacetamide--hydrogen chloride (1/1) → 5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-carbamoyl-phenyl-methyl)-amide

https://huagongshe.com/reaction/927747

Reaktionsgleichung

Beteiligte Stoffe

RolleNameHCIDEinwaage
Edukt(2S)-2-Amino-2-phenylacetamide--hydrogen chloride (1/1)HCID 22850726—
Edukt5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acidHCID 71087649—
Produkt5-Cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid ((S)-carbamoyl-phenyl-methyl)-amideHCID 71113070—

Reaktionsschritte

The title compound was synthesized in analogy to Example 280c, using 5-cyclopropyl-6-(2,2,2-trifluoro-ethoxy)-pyridine-2-carboxylic acid (Example 301a) and (S)-2-amino-2-phenyl-acetamide hydrochloride (CAN 60079-51-8) as starting materials, MS (EI): m/e=394.1 [M+H]+.

Herkunft & Nachweise

DOI10.6084/m9.figshare.5104873.v1
PatentnummerUS09290451B2
Quelldatensatzuspto-grants-2016_03
ORD IDord-8f685f90c2344560b3fd080c17f6f0e8
Quellennotizuspto-grants-2016_03