HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
(3R)-1-Azabicyclo(2.2.2)octan-3-amine → (1aRS,7bSR)-5-{2-[((R)-1-Azabicyclo[2.2.2]oct-3-yl)amino]benzenesulfonyl-amino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | (3R)-1-Azabicyclo(2.2.2)octan-3-amine | HCID 719215 | — |
| Edukt | (1aRS,7bSR)-5-(2-fluorobenzenesulfonylamino)-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid | HCID 86713249 | — |
| Produkt | (1aRS,7bSR)-5-{2-[((R)-1-Azabicyclo[2.2.2]oct-3-yl)amino]benzenesulfonyl-amino}-1,1a,2,7b-tetrahydrocyclopropa[c]chromene-4-carboxylic acid | HCID 71006993 | — |
Reaktionsschritte
Prepared by proceeding in a similar manner to Example 73, starting from (1aRS,7bSR)-5-(2-fluorobenzenesulfonylamino)-1,1a,2,7b-tetrahydrocyclopropa-[c]chromene-4-carboxylic acid (Intermediate 67) and (R)-1-azabicyclo[2.2.2]oct-3-ylamine.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US09290472B2 |
| Quelldatensatz | uspto-grants-2016_03 |
| ORD ID | ord-e8960949299747ae853689d8100d4484 |
| Quellennotiz | uspto-grants-2016_03 |