N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride → N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

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Reaktionsgleichung

[ClH:1].Cl.[CH2:3]([N:5]1[CH2:9][CH2:8][C@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4].C(N1CC[C@@H](N(C)C(=O)OCC2C=CC=CC=2)C1)C>>[ClH:1].[ClH:1].[CH2:3]([N:5]1[CH2:9][CH2:8][C@@H:7]([NH:10][CH3:11])[CH2:6]1)[CH3:4]

Komponenten

Edukt 2

HCID 86713333N-((S)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

HCID 86713337benzyl N-((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate2×

Produkt 1

HCID 86713336N-((R)-1-ethylpyrrolidin-3-yl)-N-methylamine dihydrochloride

Versuchsvorschrift

Prepared by proceeding in a similar manner to Intermediate 127, starting from benzyl N—((R)-1-ethylpyrrolidin-3-yl)-N-methylcarbamate (Intermediate 133) as a light coloured viscous oil, which was used without further characterization.

Aufarbeitung

customPrepared

Quellen und Nachweise

ORD-Eintrag: ord-74d3b56d67514f0fb685f0929e5dddcd
Quelldatensatz: uspto-grants-2016_03
DOI: 10.6084/m9.figshare.5104873.v1
Patentnummer: US09290472B2

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